5-Amino-1MQ
Also known as: 5-amino-1-methylquinolinium, 5-Amino-1-methylquinolinium iodide, 5-Amino-1MQ iodide, NNMT inhibitor (small molecule)
5-Amino-1MQ is a small synthetic molecule, a quinolinium compound, not a peptide despite how it is often marketed and categorized. It is being studied as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme found at high levels in white fat tissue. It is not an approved medicine, and its listing under weight management reflects the research area being explored, not a demonstrated use in people.
How it works
NNMT converts nicotinamide to 1-methylnicotinamide and consumes S-adenosylmethionine (SAM) in the process. Laboratory research suggests that inhibiting NNMT may leave more nicotinamide available for NAD+ production and alter methyl-group and cellular energy handling in fat tissue. These mechanisms are described from animal and cell-based studies; whether they translate into meaningful metabolic effects in humans has not been established.
Researched uses
- Studied for reduction of white adipose tissue mass in diet-induced obese mice
- Studied for effects on adipocyte size and lipid accumulation in animal and cell models
- Studied for changes in NAD+ and SAM-related metabolism in preclinical work
- Studied for potential effects on skeletal muscle and NNMT biology in aged mice
- Studied as a research tool for NNMT enzyme inhibition in obesity and metabolic disease models
Not FDA-approved for any use. There are no branded products, no published human clinical trials, and no publicly announced Investigational New Drug (IND) application. It is not on the FDA 503A list of bulk drug substances eligible for pharmacy compounding, and it is not regulated as a dietary supplement. Products sold online are typically labeled "for research use only" and fall outside the licensed pharmacy system. It should be understood as an investigational, research-only compound, not a prescription medicine.
5-Amino-1MQ providers compared
Providers that have passed our rubric review are listed first, then ordered by the total cost of a 3-month protocol. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the headline figure folds in any one-time consult or provider-review fee plus three months of membership. Use the calculator below to adjust the length and see the same total broken out.
| Provider | Sourcing | What's included | Verified | Visit provider | |
|---|---|---|---|---|---|
RxPepsDirectVerified 5-Amino-1MQ | 503A pharmacy | $279 for 3 months (est.) ≈3 vials · $80/vial incl. $39 consult | Consult fee extra · no membership | Jul 8, 2026 vial price | View |
We average every cost to a standard 3-month protocol, which our medical advisors consider the best window for comparing cost and value. Monthly plans are multiplied by 3 and 3-month programs are taken as billed; each provider's own sticker price and cadence are shown underneath.
The headline figure is the total 3-month cost: the medication plus any one-time consult or provider-review fee (for example RxPepsDirect's $39) and three months of any membership fee. Where a fee is not published we fold in what is known and flag that other fees may apply.
Per-vial providers are averaged to a 3-month protocol at roughly one vial per month (3 vials), marked "est.", with the per-vial price shown underneath. Actual vial count depends on your dose and protocol.
Prices are gathered from each provider's public pages. The "Verified" date is when we last checked the provider's sticker price; for per-vial providers it is the vial price that was verified, not the averaged 3-month total.
Value check: total cost of therapy
This is the real value comparison. A sticker price hides consult and membership fees, so this adds everything up for a full protocol of 5-Amino-1MQ and ranks by true total cost. We default to a 3-month protocol, the window our medical advisors consider best for judging value.
Per-vial providers are estimated at about one vial per month (3 vials for 3 months), plus any one-time consult. Actual vial count depends on your dose and protocol, so the real cost may run higher or lower.
Safety notes
There is no established human safety profile because no published human trials exist, so side effects, safe exposure levels, and long-term risks in people are unknown. Because it is sold outside the licensed pharmacy system under research-use-only labeling, product identity, purity, and dosing accuracy are not verified by any regulator and can vary between sources. Anyone considering it should be aware that both efficacy and safety remain unproven in humans.
5-Amino-1MQ questions
How much does 5-Amino-1MQ cost?
Across the licensed providers tracked here, a full 3-month protocol of 5-Amino-1MQ totals $279 to $279, depending on the provider, dose, and what is included. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the total folds in any one-time consult or provider-review fee and three months of membership. The providers listing 5-Amino-1MQ sell it by the vial, so the 3-month figure is an estimate of about one vial per month; the exact vial count depends on your dose and protocol. Each price shows the date the provider's sticker price was verified.
Is 5-Amino-1MQ a peptide?
No. Despite often being grouped with peptides, 5-Amino-1MQ is a small synthetic molecule, a quinolinium compound. It is not made of amino acid chains the way peptides are.
Has 5-Amino-1MQ been proven to cause weight loss in people?
No. The available evidence comes from rodent and cell-based studies. Some animal research reported reduced fat mass without changes in food intake, but no human clinical trials have been published, so effects in people are unproven.
Can I get 5-Amino-1MQ by prescription, and how is it usually sold?
There is no approved prescription form. It is not FDA-approved and is not on the list of substances eligible for pharmacy compounding. It is generally sold online under research-use-only labeling, which is outside the regulated pharmacy system, meaning quality and identity are not verified.
Related reading
- How to Get Peptides Safely and LegallyHow to get peptides through the legal, licensed pathway: prescriptions, 503A/503B pharmacies, honest evidence, and how to avoid the research-use-only gray market.
- Peptides Studied for Energy and PerformanceAn independent look at CJC-1295, ipamorelin, and MOTS-c for energy and performance: what the research shows, safety and legality, and how to find licensed care.
- Peptides and GLP-1s for Weight ManagementAn independent look at GLP-1s and peptides for weight management: what the research shows, honest limits, safety, legality, and finding licensed care.