Ipamorelin
Also known as: NNC 26-0161
Ipamorelin is a synthetic pentapeptide belonging to a class of compounds called growth hormone secretagogues. It was first described in the pharmacology literature in the late 1990s and acts as a ghrelin receptor agonist. It has not been approved by the FDA for any medical use and is classified as an investigational compound.
Often sold in blends: CJC-1295 / Ipamorelin, Tesamorelin / Ipamorelin.
How it works
Research describes ipamorelin as an agonist at the ghrelin receptor (also called the growth hormone secretagogue receptor), where it is reported to stimulate the pituitary gland to release growth hormone. Preclinical studies characterized it as more selective than some earlier secretagogues, with reports suggesting limited effect on cortisol and prolactin release at the doses tested. These are mechanistic findings from laboratory and early research and do not establish a clinical benefit.
Researched uses
- Studied for stimulation of endogenous growth hormone secretion
- Studied for effects on postoperative gastrointestinal motility (ileus) in early clinical research
- Studied in preclinical models for effects on bone metabolism
- Studied in animal models for effects on body composition
Ipamorelin is not approved by the FDA for any use. It is an investigational compound that has appeared in early clinical and preclinical research but has no marketing authorization as a medicine. In 2023 the FDA moved certain peptides, including ipamorelin, into a category that raised concerns about compounding, and it is not on the FDA list of bulk substances that compounding pharmacies may use. Products sold online as ipamorelin "for research use only" are unregulated and fall outside the licensed pharmacy system.
Ipamorelin providers compared
Providers that have passed our rubric review are listed first, then ordered by the total cost of a 3-month protocol. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the headline figure folds in any one-time consult or provider-review fee plus three months of membership. Use the calculator below to adjust the length and see the same total broken out.
| Provider | Sourcing | What's included | Verified | Visit provider | |
|---|---|---|---|---|---|
| No provider in this directory currently lists a published price for this drug. | |||||
We average every cost to a standard 3-month protocol, which our medical advisors consider the best window for comparing cost and value. Monthly plans are multiplied by 3 and 3-month programs are taken as billed; each provider's own sticker price and cadence are shown underneath.
The headline figure is the total 3-month cost: the medication plus any one-time consult or provider-review fee (for example RxPepsDirect's $39) and three months of any membership fee. Where a fee is not published we fold in what is known and flag that other fees may apply.
Per-vial providers are averaged to a 3-month protocol at roughly one vial per month (3 vials), marked "est.", with the per-vial price shown underneath. Actual vial count depends on your dose and protocol.
Prices are gathered from each provider's public pages. The "Verified" date is when we last checked the provider's sticker price; for per-vial providers it is the vial price that was verified, not the averaged 3-month total.
Safety notes
Because ipamorelin has not completed the trials required for approval, its long-term safety profile in humans is not well established. Reported effects from early research and from related growth hormone secretagogues include headache, flushing, and transient changes in blood glucose, though data are limited. Materials sold outside the licensed pharmacy system have no guarantee of identity, purity, sterility, or dose accuracy, and independent testing has found contamination and mislabeling in such products. Anyone considering it should consult a qualified clinician.
Ipamorelin questions
How much does Ipamorelin cost?
No licensed provider in this directory currently publishes a price for Ipamorelin. This page will list verified prices with their sources if that changes.
Is ipamorelin an FDA-approved medication?
No. Ipamorelin is an investigational peptide. It has not been approved by the FDA for any medical use and has no marketing authorization as a drug.
How is ipamorelin typically administered in research settings?
In the research literature ipamorelin has generally been administered by injection. This is a general description of the route studied and not a dosing recommendation. Any use should be directed by a qualified clinician.
Why does the cost and availability of ipamorelin vary so much?
Because ipamorelin is not an approved medicine and is not an FDA-listed compounding substance, there is no standard licensed supply. Material sold online varies widely in price, and because it sits outside the regulated pharmacy system its quality and identity cannot be assured.
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