Tesamorelin / Ipamorelin
Also known as: Tesamorelin/Ipamorelin, Total Recomposition, Tesa/Ipamorelin blend
Tesamorelin / Ipamorelin, sometimes sold as "Total Recomposition," is a marketing name for a blend of two peptides used as growth-hormone secretagogues. Tesamorelin is a stabilized analog of growth-hormone-releasing hormone (GHRH), and ipamorelin is a selective growth-hormone-releasing peptide (GHRP). Together they are marketed to raise the body's own growth hormone for fat-loss and lean-mass goals. Tesamorelin is an FDA-approved drug, but only for a specific condition; the combined blend is not an approved product.
What's in this blend
Tesamorelin / Ipamorelin combines the following peptides. The blend's effects and risks are those of its components together; open each for its own evidence and safety.
How it works
Tesamorelin mimics GHRH to prompt the pituitary to release growth hormone, and ipamorelin adds a ghrelin/GHRP signal on a separate receptor, so the two are paired to push growth hormone and downstream IGF-1 up through the body's own pathways. Tesamorelin's effect on reducing visceral fat is documented in its approved population; the tesamorelin-plus-ipamorelin combination has not been studied as a single product in controlled human trials.
Researched uses
- Marketed for body recomposition, fat loss, and lean mass by raising the body's own growth hormone
- Tesamorelin is FDA-approved specifically to reduce excess visceral abdominal fat in people with HIV-associated lipodystrophy
- Ipamorelin has been studied for growth-hormone release in pharmacology research
Tesamorelin is FDA-approved only to reduce visceral abdominal fat in HIV-associated lipodystrophy; using it for general recomposition is off-label, and there is no FDA-approved Tesamorelin/Ipamorelin combination product. Ipamorelin is sold as a research chemical and is not an established compounding substance. Providers listed here dispense with a prescription and describe a licensed pharmacy, but because the combination sits outside the settled rules the legal pathway is not clear-cut, so review each provider's own sourcing. Both peptides appear on the World Anti-Doping Agency (WADA) Prohibited List.
Tesamorelin / Ipamorelin providers compared
Providers that have passed our rubric review are listed first, then ordered by the total cost of a 3-month protocol. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the headline figure folds in any one-time consult or provider-review fee plus three months of membership. Use the calculator below to adjust the length and see the same total broken out.
| Provider | Sourcing | What's included | Verified | Visit provider | |
|---|---|---|---|---|---|
Ellie MDVerified Tesamorelin/Ipamorelin Injection | 503A pharmacy | $546 for 3 months $182 per month | No consult fee · no membership · shipping included | Jul 7, 2026 | View |
Better Med SpaVerified Total Recomposition (Tesamorelin/Ipamorelin) | 503A pharmacy | $1,500 for 3 months $500 per month + fees may apply (not published) | Consult fee not published · membership not published | Jul 8, 2026 | View |
TelewellnessMDVerified Tesamorelin/Ipamorelin | 503A pharmacy | pricing not published | Consult fee not published · membership not published | not checked | View |
We average every cost to a standard 3-month protocol, which our medical advisors consider the best window for comparing cost and value. Monthly plans are multiplied by 3 and 3-month programs are taken as billed; each provider's own sticker price and cadence are shown underneath.
The headline figure is the total 3-month cost: the medication plus any one-time consult or provider-review fee (for example RxPepsDirect's $39) and three months of any membership fee. Where a fee is not published we fold in what is known and flag that other fees may apply.
Per-vial providers are averaged to a 3-month protocol at roughly one vial per month (3 vials), marked "est.", with the per-vial price shown underneath. Actual vial count depends on your dose and protocol.
Prices are gathered from each provider's public pages. The "Verified" date is when we last checked the provider's sticker price; for per-vial providers it is the vial price that was verified, not the averaged 3-month total.
Value check: total cost of therapy
This is the real value comparison. A sticker price hides consult and membership fees, so this adds everything up for a full protocol of Tesamorelin / Ipamorelin and ranks by true total cost. We default to a 3-month protocol, the window our medical advisors consider best for judging value.
Safety notes
The safety of the Tesamorelin / Ipamorelin blend has not been established in humans. Growth-hormone secretagogues can raise IGF-1 and may cause water retention, joint aches, numbness, or changes in blood sugar. Tesamorelin's safety data comes from its approved HIV-lipodystrophy population, which may not transfer to healthy adults using it for recomposition, and the combination with ipamorelin is unstudied. Products sold outside the licensed pharmacy system are not verified for identity, purity, or sterility.
In the news
- Inside the booming, gray-market world of injectable peptides The Hill
Reporting on the gray market for research-use-only injectable peptides sold outside the licensed pharmacy system, and the associated health concerns.
Tesamorelin / Ipamorelin questions
How much does Tesamorelin / Ipamorelin cost?
Across the licensed providers tracked here, a full 3-month protocol of Tesamorelin / Ipamorelin totals $546 to $1,500, depending on the provider, dose, and what is included. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the total folds in any one-time consult or provider-review fee and three months of membership. Some providers listing Tesamorelin / Ipamorelin do not publish their consult or membership fees, so the top of that range may be higher. Each price shows the date the provider's sticker price was verified.
What is Tesamorelin / Ipamorelin?
It is a blend of tesamorelin (a GHRH analog) and ipamorelin (a GHRP), sometimes sold as 'Total Recomposition,' used together to raise the body's own growth hormone. Doses vary by provider.
Is it FDA-approved?
Tesamorelin is FDA-approved, but only to reduce visceral fat in HIV-associated lipodystrophy. There is no approved tesamorelin-plus-ipamorelin product, and using the blend for general recomposition is off-label and unproven.
Is it allowed in sport?
No. Both tesamorelin and ipamorelin are on the WADA Prohibited List.
Related reading
- Peptide Therapy vs TRT: An Honest ComparisonAn independent, evidence-honest look at how TRT and peptide therapy differ on FDA status, research, fertility, safety, and finding legal, prescription-based care.
- Peptides Studied for Energy and PerformanceAn independent look at CJC-1295, ipamorelin, and MOTS-c for energy and performance: what the research shows, safety and legality, and how to find licensed care.