TB-500
Also known as: Thymosin beta-4 fragment, TB4 (informal), Tβ4-related peptide
TB-500 is a synthetic peptide marketed as a fragment or analog of thymosin beta-4 (Tβ4), a naturally occurring protein involved in cell structure and movement. It is sold as a research chemical and is not a licensed medicine. Products labeled TB-500 vary in composition, and some are full-length thymosin beta-4 while others are shorter fragments.
Often sold in blends: Wolverine, Glow, Klow.
How it works
Thymosin beta-4, the parent protein, binds actin and is involved in regulating cell migration and cytoskeletal organization, which are steps in wound repair. Laboratory and animal research has reported effects on cell movement, blood vessel formation, and inflammation. Whether TB-500 as sold reproduces these mechanisms in humans has not been established in controlled clinical trials.
Researched uses
- Studied in animal models for soft-tissue and muscle injury repair
- Studied in preclinical models for tendon and ligament healing
- Studied in animal research for cardiac tissue repair after injury (as thymosin beta-4)
- Studied in preclinical models for corneal and skin wound healing
- Studied in laboratory research for effects on cell migration and angiogenesis
TB-500 is not approved by the FDA for any use in humans. It has not been reviewed for safety or effectiveness and is not available as a prescription medicine or through the licensed compounding pharmacy system. It is sold online as a "research use only" chemical, which is outside the regulated drug supply. The World Anti-Doping Agency prohibits thymosin beta-4 and related peptides in sport at all times.
TB-500 providers compared
Providers that have passed our rubric review are listed first, then ordered by the total cost of a 3-month protocol. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the headline figure folds in any one-time consult or provider-review fee plus three months of membership. Use the calculator below to adjust the length and see the same total broken out.
| Provider | Sourcing | What's included | Verified | Visit provider | |
|---|---|---|---|---|---|
Valhalla VitalityVerified TB-500 Injectable Therapy | 503A pharmacy | $897 for 3 months (est.) ≈3 vials · $299/vial | No consult fee · no membership | Jul 9, 2026 vial price | View |
We average every cost to a standard 3-month protocol, which our medical advisors consider the best window for comparing cost and value. Monthly plans are multiplied by 3 and 3-month programs are taken as billed; each provider's own sticker price and cadence are shown underneath.
The headline figure is the total 3-month cost: the medication plus any one-time consult or provider-review fee (for example RxPepsDirect's $39) and three months of any membership fee. Where a fee is not published we fold in what is known and flag that other fees may apply.
Per-vial providers are averaged to a 3-month protocol at roughly one vial per month (3 vials), marked "est.", with the per-vial price shown underneath. Actual vial count depends on your dose and protocol.
Prices are gathered from each provider's public pages. The "Verified" date is when we last checked the provider's sticker price; for per-vial providers it is the vial price that was verified, not the averaged 3-month total.
Value check: total cost of therapy
This is the real value comparison. A sticker price hides consult and membership fees, so this adds everything up for a full protocol of TB-500 and ranks by true total cost. We default to a 3-month protocol, the window our medical advisors consider best for judging value.
Per-vial providers are estimated at about one vial per month (3 vials for 3 months), plus any one-time consult. Actual vial count depends on your dose and protocol, so the real cost may run higher or lower.
Safety notes
There are no published controlled human trials establishing the safety of TB-500, so its side effect profile in people is not defined. Because it is sold as an unregulated research chemical, the actual identity, purity, dose, and sterility of any given product cannot be assumed, and contamination or mislabeling is a known concern with this market. Peptides that influence cell growth and blood vessel formation carry theoretical risks that have not been characterized in humans.
In the news
- Inside the booming, gray-market world of injectable peptides The Hill
Reporting on the gray market for research-use-only injectable peptides sold outside the licensed pharmacy system, and the associated health concerns.
TB-500 questions
How much does TB-500 cost?
Across the licensed providers tracked here, a full 3-month protocol of TB-500 totals $897 to $897, depending on the provider, dose, and what is included. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the total folds in any one-time consult or provider-review fee and three months of membership. The providers listing TB-500 sell it by the vial, so the 3-month figure is an estimate of about one vial per month; the exact vial count depends on your dose and protocol. Each price shows the date the provider's sticker price was verified.
Is TB-500 an approved drug?
No. TB-500 is not approved by the FDA for any human use and is not sold as a prescription medicine. It is marketed as a research chemical, which falls outside the regulated pharmacy system.
What is the difference between TB-500 and thymosin beta-4?
Thymosin beta-4 is a naturally occurring protein studied in laboratory and animal research. TB-500 is a synthetic product sold as a fragment or analog of it. Composition varies between products, and the two names are often used loosely in the marketplace.
Can I get TB-500 through a pharmacy or by prescription?
There is no established legitimate prescription pathway for TB-500. Products sold online as research chemicals are unregulated, and their quality, purity, and contents are not verified. Cost and access questions do not change its unapproved, investigational status.
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