Tesamorelin
Also known as: Egrifta, Egrifta SV, TH9507, tesamorelin acetate
Tesamorelin is a synthetic peptide analog of growth-hormone-releasing hormone (GHRH). It is composed of the 44-amino-acid human GHRH sequence with a chemical modification intended to increase stability in the body. It is administered by subcutaneous injection.
Often sold in blends: Tesamorelin / Ipamorelin, Tesamorelin / KPV.
How it works
According to published pharmacology, tesamorelin binds to GHRH receptors in the pituitary gland and stimulates the release of the body's own growth hormone, which in turn raises levels of insulin-like growth factor 1 (IGF-1). Research describes this as increasing pulsatile, endogenous growth hormone secretion rather than supplying growth hormone directly. The downstream effect on visceral fat is thought to involve growth-hormone-mediated lipolysis, though the full mechanism is not completely characterized.
Researched uses
- Studied for reduction of excess visceral (abdominal) fat in adults with HIV-associated lipodystrophy
- Studied for effects on IGF-1 levels and growth hormone axis function
- Studied in exploratory research for nonalcoholic fatty liver disease (NAFLD) in people with HIV
- Studied in preliminary research for cognitive and metabolic outcomes
- Investigated for effects on lipid parameters such as triglycerides
Tesamorelin is FDA-approved under the brand names Egrifta and Egrifta SV, indicated for the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy. It is a prescription-only medication. It is not approved by the FDA for general weight loss, body composition improvement in people without HIV, or anti-aging use. Products marketed online as tesamorelin "for research use only" fall outside the approved prescription pathway and are not verified for identity, purity, or sterility.
Tesamorelin providers compared
Providers that have passed our rubric review are listed first, then ordered by the total cost of a 3-month protocol. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the headline figure folds in any one-time consult or provider-review fee plus three months of membership. Use the calculator below to adjust the length and see the same total broken out.
5 of 8 providers here have completed our rubric review, so they are listed first. This reflects review status, not a quality or price ranking. Sort by price to compare on cost.
| Provider | Sourcing | What's included | Verified | Visit provider | |
|---|---|---|---|---|---|
RxPepsDirectVerified Tesamorelin | 503A pharmacy | $339 for 3 months (est.) ≈3 vials · $100/vial incl. $39 consult | Consult fee extra · no membership | Jul 8, 2026 vial price | View |
Live VitalVerified Tesamorelin Free live doctor consult | 503A pharmacy | $599 for 3 months | No consult fee · no membership · shipping included | Jul 6, 2026 | View |
TelewellnessMDVerified Tesamorelin | 503A pharmacy | $810 for 3 months (est.) ≈3 vials · $269.95/vial + fees may apply (not published) | Consult fee not published · membership not published | Jul 8, 2026 vial price | View |
Tesamorelin | 503A pharmacy | pricing not published | Consult fee not published · membership not published | not checked | View |
Tesamorelin Therapy | 503A pharmacy | pricing not published | Consult fee not published · membership not published | not checked | View |
Tesamorelin | Not yet verified | pricing not published | Consult fee not published · membership not published | not checked | View |
Tesamorelin | Not yet verified | pricing not published | Consult fee not published · membership not published | not checked | View |
Tesamorelin | Not yet verified | pricing not published | Consult fee not published · membership not published | not checked | View |
We average every cost to a standard 3-month protocol, which our medical advisors consider the best window for comparing cost and value. Monthly plans are multiplied by 3 and 3-month programs are taken as billed; each provider's own sticker price and cadence are shown underneath.
The headline figure is the total 3-month cost: the medication plus any one-time consult or provider-review fee (for example RxPepsDirect's $39) and three months of any membership fee. Where a fee is not published we fold in what is known and flag that other fees may apply.
Per-vial providers are averaged to a 3-month protocol at roughly one vial per month (3 vials), marked "est.", with the per-vial price shown underneath. Actual vial count depends on your dose and protocol.
Prices are gathered from each provider's public pages. The "Verified" date is when we last checked the provider's sticker price; for per-vial providers it is the vial price that was verified, not the averaged 3-month total.
Value check: total cost of therapy
This is the real value comparison. A sticker price hides consult and membership fees, so this adds everything up for a full protocol of Tesamorelin and ranks by true total cost. We default to a 3-month protocol, the window our medical advisors consider best for judging value.
Per-vial providers are estimated at about one vial per month (3 vials for 3 months), plus any one-time consult. Actual vial count depends on your dose and protocol, so the real cost may run higher or lower.
Safety notes
Clinical trials reported side effects including injection-site reactions, joint pain, muscle pain, swelling from fluid retention, and increases in blood glucose; the prescribing information notes potential effects on glucose tolerance and lists contraindications including active malignancy, pituitary disorders, and pregnancy. Because tesamorelin stimulates growth hormone and IGF-1, there are theoretical concerns about effects in people with a history of cancer, and it should be used under medical supervision. Material sold outside the licensed pharmacy system as "research use only" carries added risk because its actual content, dose, and sterility are not independently verified.
In the news
- Inside the booming, gray-market world of injectable peptides The Hill
Reporting on the gray market for research-use-only injectable peptides sold outside the licensed pharmacy system, and the associated health concerns.
Tesamorelin questions
How much does Tesamorelin cost?
Across the licensed providers tracked here, a full 3-month protocol of Tesamorelin totals $339 to $810, depending on the provider, dose, and what is included. We average every cost to a standard 3-month protocol, which our medical advisors consider the best basis for comparing cost and value, and the total folds in any one-time consult or provider-review fee and three months of membership. Some providers listing Tesamorelin do not publish their consult or membership fees, so the top of that range may be higher. Each price shows the date the provider's sticker price was verified.
Is tesamorelin approved for general weight loss?
No. Its only FDA-approved use is reducing excess abdominal fat in adults with HIV-associated lipodystrophy. Research has not established it as an approved treatment for general weight loss or for body composition in people without HIV.
How is tesamorelin taken?
In its approved form it is given as a subcutaneous injection under a prescription. This entry does not provide doses or a regimen; administration should be directed by a licensed clinician.
How does the cost and availability of tesamorelin generally work?
As an FDA-approved prescription drug, the branded product is obtained through licensed pharmacies with a prescription, and cost varies by insurance coverage and pharmacy. Versions sold online outside this system as research chemicals are unregulated and are not a verified or legal substitute for the prescription product.
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